On the occasion of world hypertension day 2014: A nephrology point of view

Chronic renal failure is a worldwide public health problem, and high-blood pressure is one the most important cause of dame to the kidneys. The incidence and prevalence of renal failure are increasing and are associated with poor consequences and high cost. The activity of the renin-angiotensin system (RAS) plays a central role in the pathogenesis of chronic renal failure, high-blood pressure and cardiovascular complications.[10-20] Hence, as a nephrology point of view, targeting the RAS is a logical therapeutic approach. In fact interruption of the RAS using type 1 angiotensin II receptor blockers or angiotensinconverting enzyme inhibitors alone or in combination, has become an appropriate therapeutic strategy to decrease blood pressure, proteinuria and most importantly to slow the progression of chronic renal failure.[10-20]